Restless legs syndrome: literature review

Sao Paulo Med J. 2010 May;128(3):167-70. doi: 10.1590/s1516-31802010000300008.


Restless legs syndrome is a distressing condition, with negative effects on sleep and daytime activities that affect personal, family and occupational life. The overall impact of restless legs syndrome on quality of life is comparable to that of chronic and frustrating conditions such as depression and diabetes. Misdiagnosis and inappropriate treatment may increase patients' suffering in terms of uncertainty, overuse or misuse of care services and lack of trust. Presenting a synthesis of the main topics in the literature on restless legs syndrome facilitates for a better understanding and its management in primary care settings.

Publication types

  • Review

MeSH terms

  • Humans
  • Primary Health Care
  • Quality of Life
  • Restless Legs Syndrome* / diagnosis
  • Restless Legs Syndrome* / therapy