Whole-brain perfusion imaging with 320-MDCT scanner: Reducing radiation dose by increasing sampling interval

AJR Am J Roentgenol. 2010 Nov;195(5):1183-6. doi: 10.2214/AJR.10.4230.


Objective: The purpose of this study was to investigate whether perfusion CT values obtained with a reduced-dose imaging protocol on a 320-MDCT scanner are similar to those obtained with a standard protocol.

Conclusion: Similar perfusion values at one-half the radiation dose can be obtained with the alternative algorithm used in this study.

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Body Burden
  • Brain Diseases / diagnostic imaging*
  • Cerebrovascular Circulation*
  • Contrast Media
  • Female
  • Humans
  • Iohexol
  • Male
  • Middle Aged
  • Radiation Dosage*
  • Radiographic Image Interpretation, Computer-Assisted
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*


  • Contrast Media
  • Iohexol