Patterned laser trabeculoplasty

Ophthalmic Surg Lasers Imaging. Sep-Oct 2010;41(5):538-45. doi: 10.3928/15428877-20100910-02.

Abstract

Background and objective: A novel computer-guided laser treatment for open-angle glaucoma, called patterned laser trabeculoplasty, and its preliminary clinical evaluation is described.

Patients and methods: Forty-seven eyes of 25 patients with open-angle glaucoma received 532-nm laser treatment with 100-μm spots. Power was titrated for trabecular meshwork blanching at 10 ms and sub-visible treatment was applied with 5-ms pulses. The arc patterns of 66 spots rotated automatically after each laser application so that the new pattern was applied at an untreated position.

Results: Approximately 1,100 laser spots were placed per eye in 16 steps, covering 360° of trabecular meshwork. The intraocular pressure decreased from the pretreatment level of 21.9 ± 4.1 to 16.0 ± 2.3 mm Hg at 1 month (n = 41) and remained stable around 15.5 ± 2.7 mm Hg during 6 months of follow-up (n = 30).

Conclusion: Patterned laser trabeculoplasty provides rapid, precise, and minimally traumatic (sub-visible) computer-guided treatment with exact abutment of the patterns, exhibiting a 24% reduction in intraocular pressure during 6 months of follow-up (P < .01).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Glaucoma, Open-Angle / physiopathology
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Intraocular Pressure / physiology
  • Lasers, Solid-State / therapeutic use*
  • Male
  • Middle Aged
  • Surgery, Computer-Assisted
  • Tonometry, Ocular
  • Trabecular Meshwork / physiopathology
  • Trabecular Meshwork / surgery*
  • Trabeculectomy / methods*
  • Treatment Outcome