The European Nucleotide Archive

Nucleic Acids Res. 2011 Jan;39(Database issue):D28-31. doi: 10.1093/nar/gkq967. Epub 2010 Oct 23.


The European Nucleotide Archive (ENA; is Europe's primary nucleotide-sequence repository. The ENA consists of three main databases: the Sequence Read Archive (SRA), the Trace Archive and EMBL-Bank. The objective of ENA is to support and promote the use of nucleotide sequencing as an experimental research platform by providing data submission, archive, search and download services. In this article, we outline these services and describe major changes and improvements introduced during 2010. These include extended EMBL-Bank and SRA-data submission services, extended ENA Browser functionality, support for submitting data to the European Genome-phenome Archive (EGA) through SRA, and the launch of a new sequence similarity search service.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence*
  • Databases, Nucleic Acid*
  • Europe
  • High-Throughput Nucleotide Sequencing
  • Molecular Sequence Annotation