Necropsy and sampling procedures in rodents

Methods Mol Biol. 2011:691:39-67. doi: 10.1007/978-1-60761-849-2_3.


Necropsy is a major step of most studies using laboratory animals. During necropsy, tissue and organ changes noticeable grossly can be recorded, and important tissue samples can be stored for subsequent evaluation. It is therefore important that the personnel in charge of this key experimentation step be adequately trained and aware of the study endpoints.

MeSH terms

  • Animals
  • Animals, Laboratory* / anatomy & histology
  • Autopsy / methods
  • Autopsy / veterinary*
  • Euthanasia, Animal
  • Female
  • Histological Techniques
  • Humans
  • Male
  • Mice
  • Organ Size
  • Rats
  • Species Specificity
  • Specimen Handling