Recent advances in the treatment of eosinophilic esophagitis

Expert Rev Clin Immunol. 2010 Nov;6(6):929-37. doi: 10.1586/eci.10.65.

Abstract

First described nearly 20 years ago, eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus characterized by eosinophilic infiltration of the esophageal epithelium. Over 50% of the current literature on EoE has been published in the last 3 years, signaling both a rising incidence and increased recognition of this disorder. Treatment options available for patients with EoE include dietary management and/or pharmacologic therapy. An individualized approach to treatment is preferred, with an emphasis on patient-parental preference. The objective of this article is to discuss the current and future treatment options for EoE.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Diet Therapy / trends
  • Eosinophilic Esophagitis / immunology
  • Eosinophilic Esophagitis / therapy*
  • Humans
  • Immunotherapy* / trends
  • Interleukin-13 / immunology
  • Interleukin-5 / immunology
  • Mucous Membrane / drug effects
  • Mucous Membrane / immunology*
  • Mucous Membrane / pathology
  • Patient Preference
  • Precision Medicine
  • Proton Pump Inhibitors / therapeutic use*
  • Th1-Th2 Balance / drug effects

Substances

  • Antibodies, Monoclonal
  • Interleukin-13
  • Interleukin-5
  • Proton Pump Inhibitors