Characterization of alpha and beta crystalline forms of nicardipine hydrochloride

J X Yan; P Giunchedi

Characterization of alpha and beta crystalline forms of nicardipine hydrochloride

Boll Chim Farm. 1990 Sep;129(9):276-8.

Authors

J X Yan¹, P Giunchedi

Affiliation

¹ Dept. of Pharmaceutical Chemistry, University of Pavia, Italy.

PMID: 2098055

Abstract

The aim of this work was the characterization of alpha and beta crystalline forms of nicardipine hydrochloride (coronary vasodilator drug) by means of DSC analysis, X-ray diffraction patterns, TLC analysis and IR spectroscopy. The results obtained show that it is possible to distinguish the two forms by means of these techniques.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, Thin Layer
Crystallization
Nicardipine / chemistry*
Solubility
Spectrophotometry, Infrared
X-Ray Diffraction

Substances

Nicardipine