Single exposure fabrication and manipulation of 3D hydrogel cell microcarriers

Lab Chip. 2011 Jan 7;11(1):48-51. doi: 10.1039/c0lc00369g. Epub 2010 Oct 27.

Abstract

We present a simple and high-throughput method for fabricating free-floating hydrogel cell microcarriers using single exposure UV patterning. We also demonstrate magnetic manipulation of the free-floating cell microcarriers using a magnetic nanoparticle-embedded structure for an active agitation and a solution exchange.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Equipment Design
  • HeLa Cells
  • Humans
  • Hydrogels / chemistry*
  • Magnetics
  • Microtechnology / methods*
  • Nanoparticles / chemistry
  • Tissue Array Analysis / instrumentation*
  • Ultraviolet Rays

Substances

  • Hydrogels