Sodium thiosulfate treatment of tumoral calcinosis in patients with end-stage renal disease

Ren Fail. 1990;12(4):213-9. doi: 10.3109/08860229009060727.


Three patients (2 male and 1 female) undergoing maintenance hemodialysis for more than 4 years with tumoral calcifications were treated by sodium thiosulfate. All patients had periarticular and soft tissue calcification. A considerable regression of calcified masses with concurrent clinical improvement was noted in 2 of the 3 patients.

MeSH terms

  • Calcinosis / drug therapy*
  • Female
  • Humans
  • Kidney Failure, Chronic / complications*
  • Kidney Failure, Chronic / therapy
  • Male
  • Renal Dialysis
  • Thiosulfates / therapeutic use*


  • Thiosulfates
  • sodium thiosulfate