Effects of Lactobacillus gasseri BNR17 on body weight and adipose tissue mass in diet-induced overweight rats

J Microbiol. 2010 Oct;48(5):712-4. doi: 10.1007/s12275-010-0363-8. Epub 2010 Nov 3.


We investigated the weight-gain suppressive effect of Lactobacillus gasseri BNR17 isolated from human breast milk. Rats were fed a high-carbohydrate diet and administered BNR17 (BNR17 group) twice daily for twelve weeks. Changes were observed in body weight and white adipose tissue mass. The percent increase in body weight (P=0.0331) and fat pad mass (P<0.01) was significantly lower in the BNR17 group, and the FER was moderately lower (P=0.0769). These data suggest that BNR17 can prevent diet-induced overweight and may become an alternative method for treating weight problems and obesity.

MeSH terms

  • Adipose Tissue / pathology*
  • Animals
  • Diet Therapy / methods*
  • Humans
  • Lactobacillus / growth & development*
  • Lactobacillus / isolation & purification
  • Milk, Human / microbiology
  • Overweight / therapy*
  • Probiotics / administration & dosage*
  • Rats
  • Treatment Outcome