Abstract
A mild Negishi cross-coupling of 2-heterocyclic organozinc reagents and aryl chlorides is described. The use of Pd(2)(dba)(3) and X-Phos as a ligand provides high yields for many examples. An efficient method to generate the organozinc reagents at room temperature is also demonstrated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cross-Linking Reagents
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Hydrocarbons, Chlorinated / chemistry*
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Indicators and Reagents
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Organometallic Compounds / chemical synthesis*
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Organometallic Compounds / chemistry*
Substances
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Cross-Linking Reagents
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Hydrocarbons, Chlorinated
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Indicators and Reagents
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Organometallic Compounds