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Case Reports
. 2010 Nov 4;363(19):1847-51.
doi: 10.1056/NEJMcps0904937.

Clinical problem-solving. Bitter pills

Yonatan H Grad  1 , Julian L Seifter, Bruce D Levy, Joseph Loscalzo
Affiliations
Case Reports

Clinical problem-solving. Bitter pills

Yonatan H Grad et al. N Engl J Med. .
No abstract available

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1. Biopsy Specimen
Periodic acid–Schiff staining of a kidney-biopsy specimen reveals diffuse interstitial edema and inflammation (Panel A); at higher magnification (Panel B), a sample stained with hematoxylin and eosin shows invasion of the tubular structures and interstitium by a mixed inflammatory infiltrate with many lymphocytes and eosinophils. An electron micrograph (Panel C) reveals thin glomerular basement membranes (arrow). Images courtesy of Dr. Helmut Rennke.
See this image and copyright information in PMC

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References

    1. Baker RJ, Pusey CD. The changing profile of acute tubulointerstitial nephritis. Nephrol Dial Transplant. 2004;19:8–11. - PubMed
    1. Michel DM, Kelly CJ. Acute interstitial nephritis. J Am Soc Nephrol. 1998;9:506–15. - PubMed
    1. Brewster UC, Perazella MA. Proton pump inhibitors and the kidney: critical review. Clin Nephrol. 2007;68:65–72. - PubMed
    1. Clarkson MR, Giblin L, O’Connell FP, et al. Acute interstitial nephritis: clinical features and response to corticosteroid therapy. Nephrol Dial Transplant. 2004;19:2778–83. - PubMed
    1. González E, Gutiérrez E, Galeano C, et al. Early steroid treatment improves the recovery of renal function in patients with drug-induced acute interstitial nephritis. Kidney Int. 2008;73:940–6. - PubMed

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