Accuracy of magnetic resonance imaging in ovarian tumor: a systematic quantitative review

Am J Obstet Gynecol. 2011 Jan;204(1):67.e1-10. doi: 10.1016/j.ajog.2010.08.031. Epub 2010 Nov 3.


Objective: To estimate the diagnostic accuracy of magnetic resonance in ovarian tumors.

Study design: A quantitative systematic review was performed. Studies that compared magnetic resonance and paraffin sections within subjects for diagnosis of ovarian tumors were included.

Results: Fifteen primary studies were analyzed, which included 1267 ovarian masses. For borderline or malignant ovarian cancer vs benign ovarian lesions, the pooled likelihood ratio for the occurrence of a positive magnetic resonance result was 6.6 (95% confidence interval, 4.7-9.2) and the posttest probability for borderline or malignant diagnosis was 77% (95% confidence interval, 70-82). Because specificity and likelihood ratio positive were heterogeneous, a random effect model was used and a summary receiver operating characteristic curve was generated. For borderline or malignant ovarian cancer vs benign ovarian lesions, the area under curve was 0.9526.

Conclusion: Magnetic resonance seems to be a useful preoperative test for predicting the diagnosis of pelvic masses.

Publication types

  • Evaluation Study
  • Meta-Analysis
  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Confidence Intervals
  • Female
  • Humans
  • Likelihood Functions
  • Magnetic Resonance Imaging / standards*
  • Ovarian Neoplasms / pathology*
  • Paraffin Embedding / standards*