Post-surgical treatment of melanoma in situ of the vulva with imiquimod

J Obstet Gynaecol Can. 2010 Aug;32(8):771-4. doi: 10.1016/s1701-2163(16)34619-9.


Background: Melanoma in situ is a rare malignant lesion of the vulva. The standard treatment is surgical excision.

Case: We describe a case of melanoma in situ of the vulva in a 72-year-old woman that reoccurred after surgical excision and was treated successfully with topical 5% imiquimod.

Conclusion: There may be a role for imiquimod in treating melanoma in situ of the vulva.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aminoquinolines / therapeutic use*
  • Antineoplastic Agents / therapeutic use*
  • Combined Modality Therapy
  • Female
  • Humans
  • Imiquimod
  • Melanoma / drug therapy*
  • Melanoma / surgery*
  • Vulvar Neoplasms / drug therapy*
  • Vulvar Neoplasms / surgery*


  • Aminoquinolines
  • Antineoplastic Agents
  • Imiquimod