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Review
. 2010 Sep;15 Suppl 1:1-6.
doi: 10.1111/j.1523-5378.2010.00779.x.

Epidemiology of Helicobacter Pylori Infection and Public Health Implications

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Review

Epidemiology of Helicobacter Pylori Infection and Public Health Implications

Alexander C Ford et al. Helicobacter. .

Abstract

This article summarizes the published literature concerning the epidemiology and public health implications of Helicobacter pylori infection published from April 2009 through March 2010. Prevalence of infection varied between 7 and 87% and was lower in European studies. All retrieved studies examining transmission of infection concluded that spread is from person-to-person. One study collecting stool and vomitus samples from patients with acute gastroenteritis detected H. pylori DNA in 88% of vomitus and 74% of stool samples. Proposed risk factors for infection included male gender, increasing age, shorter height, tobacco use, lower socioeconomic status, obesity, and lower educational status of the parents in studies conducted among children. Decision analysis models suggest preventing acquisition of H. pylori, via vaccination in childhood, could be cost-effective and may reduce incidence of gastric cancer by over 40%. As yet, no country has adopted public health measures to treat infected individuals or prevent infection in populations at risk.

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