Novel and efficient one-pot five- and six-component reactions for the stereoselective synthesis of highly functionalized enaminones and dithiocarbamates

Morteza Bararjanian; Saeed Balalaie; Frank Rominger; Barahman Movassagh; Hamid Reza Bijanzadeh

doi:10.1007/s11030-010-9286-x

Novel and efficient one-pot five- and six-component reactions for the stereoselective synthesis of highly functionalized enaminones and dithiocarbamates

Mol Divers. 2011 May;15(2):583-94. doi: 10.1007/s11030-010-9286-x. Epub 2010 Nov 12.

Authors

Morteza Bararjanian¹, Saeed Balalaie, Frank Rominger, Barahman Movassagh, Hamid Reza Bijanzadeh

Affiliation

¹ Peptide Chemistry Research Group, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran, Iran.

PMID: 21072590
DOI: 10.1007/s11030-010-9286-x

Abstract

Efficient methods for stereoselective synthesis of polyfunctional (E)-enaminones and (Z)-dithiocarbamates via one-pot five- and six-component sequential Ugi/Nucleophilic addition reactions are described. High yields and high bond forming efficiency, and simple operations are the advantages of this method.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amines / chemical synthesis*
Amines / chemistry
Combinatorial Chemistry Techniques* / methods
Models, Chemical
Stereoisomerism
Structure-Activity Relationship
Thiocarbamates / chemical synthesis*
Thiocarbamates / chemistry*

Substances

Amines
Thiocarbamates