Three-dimensional self-assembly of graphene oxide and DNA into multifunctional hydrogels

ACS Nano. 2010 Dec 28;4(12):7358-62. doi: 10.1021/nn1027104. Epub 2010 Nov 16.


Graphene and its functionalized derivatives are unique and versatile building blocks for self-assembly to fabricate graphene-based functional materials with hierarchical microstructures. Here we report a strategy for three-dimensional self-assembly of graphene oxide sheets and DNA to form multifunctional hydrogels. The hydrogels possess high mechanical strength, environmental stability, and dye-loading capacity, and a exhibit self-healing property. This study provides a new insight for the assembly of functionalized graphene with other building blocks, especially biomolecules, which will help rational design and preparation of hierarchical graphene-based materials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Buffers
  • DNA / chemistry*
  • Graphite / chemistry*
  • Hydrogels / chemistry*
  • Hydrogen-Ion Concentration
  • Models, Molecular
  • Molecular Conformation*
  • Nucleic Acid Denaturation
  • Oxides / chemistry*
  • Sodium Chloride / chemistry
  • Solvents / chemistry


  • Buffers
  • Hydrogels
  • Oxides
  • Solvents
  • Sodium Chloride
  • Graphite
  • DNA