Chromosome structure at interfaces between major chromatin types: alpha- and beta-heterochromatin

Bioessays. 1990 Jan;12(1):1-6. doi: 10.1002/bies.950120102.


The chromocenter of Drosophila polytene chromosomes, which consists of two major chromatin types, has long been a troublesome region in molecular terms. The recent microcloning of part of this region, the isolation of a monoclonal antibody to a beta-heterochromatin binding protein, and new in situ studies now shed a little more light on this chromosomal region.

Publication types

  • Review

MeSH terms

  • Animals
  • Chromatin / ultrastructure*
  • Chromosomes / ultrastructure*
  • Drosophila / genetics*
  • Drosophila melanogaster / genetics
  • Heterochromatin / ultrastructure*
  • Mitosis
  • Models, Structural


  • Chromatin
  • Heterochromatin