Anomalous origin of the left coronary artery from the pulmonary artery in Alagille syndrome

Congenit Heart Dis. Sep-Oct 2010;5(5):462-4. doi: 10.1111/j.1747-0803.2010.00386.x.


Alagille syndrome is a dominantly inherited multisystem disorder involving multiple organs including the liver, heart, eyes, face, and skeleton. Congenital heart defects, the majority of which are right-sided, contribute significantly to the mortality of these patients. We report a patient with Alagille syndrome who presented with mitral valve regurgitation requiring valvuloplasty and subsequent mitral valve replacement. The patient was ultimately diagnosed with anomalous origin of the left coronary artery from the pulmonary artery and underwent successful reimplantation.

Publication types

  • Case Reports

MeSH terms

  • Alagille Syndrome / complications*
  • Alagille Syndrome / diagnosis
  • Alagille Syndrome / therapy
  • Catheterization
  • Coronary Vessel Anomalies / complications*
  • Coronary Vessel Anomalies / diagnosis
  • Coronary Vessel Anomalies / therapy
  • Female
  • Heart Valve Prosthesis Implantation
  • Humans
  • Infant
  • Mitral Valve Insufficiency / congenital*
  • Mitral Valve Insufficiency / diagnosis
  • Mitral Valve Insufficiency / therapy
  • Pulmonary Artery / abnormalities*
  • Pulmonary Artery / surgery
  • Replantation
  • Treatment Outcome
  • Vascular Surgical Procedures