A new kaolin-based hemostatic bandage use after coronary diagnostic and interventional procedures

Int J Cardiol. 2012 Apr 5;156(1):53-4. doi: 10.1016/j.ijcard.2010.10.030. Epub 2010 Nov 18.

Abstract

Background: Bleeding and vascular access site complications are an important cause of morbidity after percutaneous femoral procedures. Together with collagen-based and suture-based vascular closure devices, new hemostatic dressings have been developed to control heavy bleeding.

Aim of study: To evaluate safety and efficacy results of the first clinical QuikClot Interventional Hemostatic Bandage use for femoral artery closure after diagnostic or interventional procedures.

Methods: The first European safety study was performed at the Centro Cardiologico Monzino in Milan, Italy, on January 2010. Forty consecutive patients (75% male, mean age 68 ± 11years) undergoing diagnostic angiography (62%) or PCI (38%) by femoral approach with a 6- (90%) or 7-Fr (10%) size introducer, received arterial sheath removal with the QuikClot Interventional gauze use. The mean ACT value at hemostasis time was 138 ± 24s (range 95-186s). Hemostasis was achieved in a mean time of 4.9 ± 0.5 min. Only one hemostasis failure occurred requiring prolonged mechanical compression. Neither major bleeding, re-bleeding nor hematoma occurred after early (4h after procedure) ambulation.

Conclusions: QuikClot Interventional Bandage obtained prompt hemostasis and allowed for an early ambulation without clinical complications.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Bandages*
  • Coronary Angiography / adverse effects*
  • Coronary Angiography / methods
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / methods
  • Female
  • Femoral Artery / surgery
  • Hemorrhage / prevention & control
  • Hemostatic Techniques*
  • Hemostatics / administration & dosage*
  • Humans
  • Kaolin / administration & dosage*
  • Male
  • Middle Aged

Substances

  • Hemostatics
  • Kaolin