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Editorial
. 2010 Nov 15;9(22):4419-21.
doi: 10.4161/cc.9.22.14051. Epub 2010 Nov 15.

Genome-wide RNAi Screen Discovers Functional Coupling of Alternative Splicing and Cell Cycle Control to Apoptosis Regulation

Free PMC article
Editorial

Genome-wide RNAi Screen Discovers Functional Coupling of Alternative Splicing and Cell Cycle Control to Apoptosis Regulation

Qingqing Wang et al. Cell Cycle. .
Free PMC article

Figures

Figure 1
Figure 1
(A) Splicing reporters Bcl-x and Mcl1 are schematized. Green rectangles are exons, with gray areas depicting alternative spliced region. Black lines between rectangles are introns. Arrows denote translational start site. Inserted PTCs exclusive to long isoforms are shown by red “stop signs.” (B) A model of the functional coupling of cell cycle control and AS to apoptosis regulation from our genome-wide screen is shown.

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