Sex differences: implications for the obesity-asthma association

Exerc Sport Sci Rev. 2011 Jan;39(1):48-56. doi: 10.1097/JES.0b013e318201f0c4.


We have demonstrated in several studies that obesity and adipokines are more strongly associated with asthma in women than in men. The reason for this controversial sex difference is not known. Based on our previous studies, we hypothesize that sex-related differences in ectopic fat may explain the obesity-asthma association in women.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Adipokines / blood*
  • Asthma / epidemiology*
  • Body Fat Distribution*
  • Comorbidity
  • Exercise
  • Female
  • Humans
  • Male
  • Obesity / epidemiology*
  • Phenotype
  • Risk Factors
  • Sedentary Behavior
  • Sex Factors*


  • Adipokines