Human listeriosis in Britain, 1967-85, a summary of 722 cases. 2. Listeriosis in non-pregnant individuals, a changing pattern of infection and seasonal incidence

Epidemiol Infect. 1990 Apr;104(2):191-201. doi: 10.1017/s0950268800059355.

Abstract

Clinical information was collected on 722 cases of Listeria monocytogenes infections in humans occurring in Britain between 1967 and 1985. This series comprised 34% (248 cases) associated with pregnancy and 66% (474 cases) in non-pregnant adults and juveniles. The cases not associated with pregnancy comprised: 76% in patients with severe underlying illness (of which 34% had central nervous system infections, and 42% bacteraemia without involvement of the central nervous system); 21% in previously healthy individuals (of whom 18% had meningitis); and 3% in patients without bacteraemia or involvement of the central nervous system. Cases occurred most often in male patients over 40 years of age. The overall mortality was 44%. Overall, the pattern of infection has altered to a disease of higher incidence, affecting most often susceptible non-pregnant individuals and the unborn. An annual increase in incidence of listeriosis occurred in the autumn in all categories of patients.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Central Nervous System Diseases / epidemiology*
  • Central Nervous System Diseases / mortality
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Infant
  • Listeria monocytogenes
  • Listeriosis / epidemiology*
  • Listeriosis / mortality
  • Male
  • Middle Aged
  • Seasons
  • Sepsis / epidemiology*
  • Sepsis / mortality
  • Sex Factors
  • United Kingdom / epidemiology