The objective of this work was to evaluate the possibility to use combined therapy including application of transcranial pulsed electrostimulation and an alternating electrostatic field to the treatment of "restless legs" syndrome (RLS) in patients with Parkinson disease. A total of 31 patients with this syndrome were available for observation. A single course of combined therapy resulted in a substantial (60.4%) alleviation of painful sensation in 20 patients. Depression and anxiety decreased by 53.56% and 52.38% respectively. Accordingly, the quality of life increased (6.48%). In the 11 patients of the control group, these changes were much less pronounced; that is, painful sensation, depression, and anxiety decreased by 8.15%, 5.17%, and 10.11% respectively. It is concluded that combined therapy including application of transcranial pulsed electrostimulation and an alternating electrostatic field produced highly beneficial effect in patients with Parkinson disease and restless legs syndrome.