Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 30 (3), 260-6

Primate Evolution at the DNA Level and a Classification of Hominoids


Primate Evolution at the DNA Level and a Classification of Hominoids

M Goodman et al. J Mol Evol.


The genetic distances among primate lineages estimated from orthologous noncoding nucleotide sequences of beta-type globin loci and their flanking and intergenic DNA agree closely with the distances (delta T50H values) estimated by cross hybridization of total genomic single-copy DNAs. These DNA distances and the maximum parsimony tree constructed for the nucleotide sequence orthologues depict a branching pattern of primate lineages that is essentially congruent with the picture from phylogenetic analyses of morphological characters. The molecular evidence, however, resolves ambiguities in the morphological picture and provides an objective view of the cladistic position of humans among the primates. The molecular data group humans with chimpanzees in subtribe Hominina, with gorillas in tribe Hominini, orangutans in subfamily Homininae, gibbons in family Hominidae, Old World monkeys in infraorder Catarrhini, New World monkeys in semisuborder Anthropoidea, tarsiers in suborder Haplorhini, and strepsirhines (lemuriforms and lorisiforms) in order Primates. A seeming incongruency between organismal and molecular levels of evolution, namely that morphological evolution appears to have speeded up in higher primates, especially in the lineage to humans, while molecular evolution has slowed down, may have the trivial explanation that relatively small genetic changes may sometimes result in marked phenotypic changes.

Similar articles

See all similar articles

Cited by 27 articles

See all "Cited by" articles


    1. Science. 1967 Jan 20;155(3760):279-84 - PubMed
    1. J Mol Biol. 1989 Jan 5;205(1):85-90 - PubMed
    1. Mol Biol Evol. 1988 May;5(3):217-36 - PubMed
    1. Nature. 1980 Jul 24;286(5771):420-3 - PubMed
    1. J Mol Biol. 1988 Sep 20;203(2):439-55 - PubMed

Publication types

LinkOut - more resources