Preoperative bowel preparation for patients undergoing elective colorectal surgery: a clinical practice guideline endorsed by the Canadian Society of Colon and Rectal Surgeons
- PMID: 21092431
- PMCID: PMC2993029
Preoperative bowel preparation for patients undergoing elective colorectal surgery: a clinical practice guideline endorsed by the Canadian Society of Colon and Rectal Surgeons
Abstract
Background: Despite evidence that mechanical bowel preparation (MBP) does not reduce the rate of postoperative complications, many surgeons still use MBP before surgery. We sought to appraise and synthesize the available evidence regarding preoperative bowel preparation in patients undergoing elective colorectal surgery.
Methods: We searched MEDLINE, EMBASE and Cochrane Databases to identify randomized controlled trials (RCTs) comparing patients who received a bowel preparation with those who did not. Two authors reviewed the abstracts to identify articles for critical appraisal. We used the methods of the United States Preventive Services Task Force to grade study quality and level of evidence, as well as formulate the final recommendations. Outcomes assessed included postoperative infectious complications, such as anastomotic dehiscence and superficial surgical site infections.
Results: Our review identified 14 RCTs and 8 meta-analyses. Based on the quality and content of these original manuscripts, we formulated 6 recommendations for various aspects of bowel preparation in patients undergoing elective colorectal surgery.
Conclusion: Taking into account the lack of difference in postoperative infectious complication rates when MBP is omitted and the adverse effects of MBP, we believe that, based on the literature, MBP before surgery should be omitted.
Contexte: En dépit de données probantes indiquant que la préparation mécanique de l’intestin (PMI) ne réduit pas le taux de complications postopératoires, beaucoup de chirurgiens utilisent toujours la PMI avant l’intervention. Nous avons cherché à évaluer et résumer les données probantes disponibles sur la préparation préopératoire de l’intestin chez les patients qui subissent une chirurgie colorectale élective.
Méthodes: Nous avons effectué une recherche dans MEDLINE, EMBASE et les bases de données Cochrane pour repérer les essais contrôlés randomisés (ECR) où l’on a comparé les patients qui ont reçu une préparation de l’intestin à ceux qui n’en ont pas reçu. Deux auteurs ont analysé les résumés pour repérer les articles à soumet-tre à une évaluation critique. Nous avons utilisé les méthodes du Groupe de travail sur les services de prévention des États-Unis (United States Preventive Services Task Force pour évaluer la qualité de l’étude et le niveau des éléments probants, et pour formuler des recommandations finales. Les résultats évalués ont inclus les complications infectieuses postopératoires comme la déhiscence de l’anastomose et les infections superficielles du site chirurgical.
Résultats: Notre étude a permis de repérer 14 ECR et 8 méta-analyses. Compte tenu de la qualité et du contenu de ces manuscrits originaux, nous avons formulé 6 recommandations portant sur divers aspects de la préparation de l’intestin chez les patients qui subissent une chirurgie colorectale élective.
Conclusion: Comme il n’y avait pas de différence au niveau des taux de complications infectieuses postopératoires lorsque la PMI est omise et compte tenu des effets indésirables de la PMI, nous sommes d’avis, en nous basant sur les publications, qu’il faudrait abandonner la PMI avant les interventions chirurgicales.
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