[Nutrition and age-related macular degeneration]

J Fr Ophtalmol. 2010 Dec;33(10):749-57. doi: 10.1016/j.jfo.2010.09.011. Epub 2010 Nov 18.
[Article in French]


Age-related macular degeneration is a growing burden disease with a high prevalence in elderly: it is the first cause of blindness in developped countries. It is a multifactorial disease with genetic factors and nutritional factors. Carotenoids, lutein and zeaxanthin are components of macular pigment and they have a filter role for blue light and an antioxidant role. Other nutritional factors might play a role as antioxidants: zinc, selenium, vitamin E, vitamin C… which lead to the ARED Study. It is the only one study with proven positive effects on the disease progression (stages 3 and 4). A high glycemic index increases oxidative stress. Long chain omega-3 polyunsaturated fatty acids have a protective effect. Available data are presented and discussed. These are new preventive issues.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Carotenoids / therapeutic use
  • Diet*
  • Fatty Acids, Omega-3 / therapeutic use
  • Humans
  • Macular Degeneration / prevention & control*


  • Fatty Acids, Omega-3
  • Carotenoids