Oral infections and antibiotic therapy

Otolaryngol Clin North Am. 2011 Feb;44(1):57-78, v. doi: 10.1016/j.otc.2010.10.003.


Oral infections commonly originate from an odontogenic source in adults and from tonsil and lymphatic sources in children. Odontogenic infections arise from advanced dental caries or periodontal disease. Oral trauma, radiation injury, chemotherapy mucositis, salivary gland infection, lymph node abscess, and postoperative infection are potential nonodontogenic sources of infections that could potentially be life threatening. This article reviews the serious nature and potential danger that exists from oral infection and the antibiotics available to treat them are reviewed. Successful treatment requires an understanding of the microflora, the regional anatomy, the disease process, the treatment methods available, and interdisciplinary team collaboration.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / therapeutic use*
  • Antifungal Agents / therapeutic use
  • Bacterial Infections / drug therapy*
  • Focal Infection, Dental / drug therapy*
  • Herpes Simplex / drug therapy
  • Humans
  • Male
  • Mouth / microbiology
  • Mouth Diseases / drug therapy*
  • Mycoses / drug therapy


  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents