Blast-induced mild traumatic brain injury

Psychiatr Clin North Am. 2010 Dec;33(4):757-81. doi: 10.1016/j.psc.2010.08.001. Epub 2010 Oct 15.


Traumatic brain injury (TBI) has been a major cause of mortality and morbidity in the wars in Iraq and Afghanistan. Blast exposure has been the most common cause of TBI, occurring through multiple mechanisms. What is less clear is whether the primary blast wave causes brain damage through mechanisms that are distinct from those common in civilian TBI and whether multiple exposures to low-level blast can lead to long-term sequelae. Complicating TBI in soldiers is the high prevalence of posttraumatic stress disorder. At present, the relationship is unclear. Resolution of these issues will affect both treatment strategies and strategies for the protection of troops in the field.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Afghan Campaign 2001-
  • Blast Injuries / complications*
  • Blast Injuries / epidemiology
  • Brain Injuries / complications
  • Brain Injuries / epidemiology
  • Brain Injuries / etiology*
  • Humans
  • Iraq War, 2003-2011
  • Military Personnel*
  • Prevalence
  • Severity of Illness Index
  • Stress Disorders, Post-Traumatic / epidemiology
  • Stress Disorders, Post-Traumatic / etiology*
  • Warfare*