Saliva as a diagnostic fluid

Dent Clin North Am. 2011 Jan;55(1):159-78. doi: 10.1016/j.cden.2010.08.004.


Salivary diagnostics is a dynamic and emerging field utilizing nanotechnology and molecular diagnostics to aid in the diagnosis of oral and systemic diseases. In this article the author critically reviews the latest advances using oral biomarkers for disease detection. The use of oral fluids is broadening perspectives in clinical diagnosis, disease monitoring, and decision making for patient care. Important elements determining the future possibilities and challenges in this field are also discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers / analysis*
  • Diagnostic Techniques and Procedures
  • Humans
  • Saliva / chemistry*
  • Saliva / metabolism
  • Salivary Proteins and Peptides / analysis*
  • Sensitivity and Specificity


  • Biomarkers
  • Salivary Proteins and Peptides