Abstract
Purified midgestation murine trophoblast cannot be killed by a variety of cell-mediated effector mechanisms, with the exception of highly lytic effectors such as lymphokine-activated killer cells. We now report that this trophoblast population is also resistant to tumor necrosis factor (TNF)-alpha.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Analysis of Variance
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Animals
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Cycloheximide / pharmacology
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Cytotoxins / pharmacology
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Dactinomycin / pharmacology
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In Vitro Techniques
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Interferon-gamma / pharmacology
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Mice
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Trophoblasts / physiology*
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Tumor Necrosis Factor-alpha / pharmacology*
Substances
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Cytotoxins
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Tumor Necrosis Factor-alpha
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Dactinomycin
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Interferon-gamma
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Cycloheximide