Sex determination compared in Drosophila and Caenorhabditis

Nature. 1990 Apr 19;344(6268):721-8. doi: 10.1038/344721a0.


Fruitflies and nematodes show many similarities in the general organization of the gene networks that control sexual dimorphism and dosage compensation. In contrast, the underlying molecular mechanisms appear to be very different in these two species. Developmental processes such as sex determination need not be strongly conserved in evolution.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Caenorhabditis / genetics*
  • Dosage Compensation, Genetic
  • Drosophila melanogaster / genetics*
  • Female
  • Genes, Regulator
  • Germ Cells
  • Male
  • Phenotype
  • Sex Determination Analysis*
  • X Chromosome