Posterior lattice degeneration characterized by spectral domain optical coherence tomography

Retina. 2011 Mar;31(3):492-6. doi: 10.1097/IAE.0b013e3181ed8dc9.


Purpose: The purpose of this study was to use high-resolution spectral domain optical coherence tomography in the characterization of retinal and vitreal morphological changes overlying posterior lattice degeneration.

Methods: A cross-sectional retrospective analysis was performed on 13 eyes of 13 nonconsecutive subjects with posterior lattice degeneration seen at the New England Eye Center, Tufts Medical Center between October 2009 and January 2010. Spectral domain optical coherence tomography images taken through the region of lattice degeneration were qualitatively analyzed.

Results: Four characteristic changes of the retina and vitreous were seen in the 13 eyes with lattice degeneration: 1) anterior/posterior U-shaped vitreous traction; 2) retinal breaks; 3) focal retinal thinning; and 4) vitreous membrane formation. The morphologic appearance of vitreous traction and retinal breaks were found to be consistent with previous histologic reports.

Conclusion: It is possible to image posterior lattice degeneration in many eyes using spectral domain optical coherence tomography and to visualize the spectrum of retinal and vitreous changes throughout the area of lattice degeneration.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Aged
  • Atrophy
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retina / pathology*
  • Retinal Degeneration / diagnosis*
  • Retinal Perforations / diagnosis
  • Retrospective Studies
  • Tomography, Optical Coherence*
  • Vitreous Body / pathology*