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Clinical Trial
. 2010 Nov 2;5:313-6.
doi: 10.2147/CIA.S13432.

The Effect of Phosphatidylserine-Containing omega-3 Fatty Acids on Memory Abilities in Subjects With Subjective Memory Complaints: A Pilot Study

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Clinical Trial

The Effect of Phosphatidylserine-Containing omega-3 Fatty Acids on Memory Abilities in Subjects With Subjective Memory Complaints: A Pilot Study

Yael Richter et al. Clin Interv Aging. .
Free PMC article

Abstract

Objective: To evaluate for the first time the efficacy of safe-sourced phosphatidylserine-containing omega-3 long chain polyunsaturated fatty acid (PS-omega-3) in improving memory abilities.

Methods: PS-omega-3 was administered daily for 6 weeks to eight elderly volunteers with subjective memory complaints. The Cognitive Drug Research test battery was used to assess the effect on their cognitive abilities.

Results: PS-omega-3 supplementation resulted in 42% increase in the ability to recall words in the delayed condition.

Conclusion: PS-omega-3 may have a favorable effect on memory in subjects with subjective memory complaints. PS-omega-3 may serve as a safe alternative to phosphatidylserine extracted from bovine cortex.

Keywords: cognitive; memory; omega-3; phosphatidylserine.

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References

    1. Clark CR, Paul RH, Williams LM, et al. Standardized assessment of cognitive functioning during development and aging using an automated touchscreen battery. Arch Clin Neuropsychol. 2006;21:449–467. - PubMed
    1. Gordon E, Cooper N, Rennie C, Hermens D, Williams LM. Integrative neuroscience: the role of a standardized database. Clin EEG Neurosci. 2005;36:64–75. - PubMed
    1. Fünfgeld EW, Nedwidek P. Neurohomologous phosphatidylserine in parkinsonian patients with associated disorders of cerebral metabolism: results of a pilot study. Clin Trials J. 1987;24:42–61.
    1. Pepeu G, Pepeu IM, Amaducci L. A review of phosphatidylserine pharmacological and clinical effects. Is phosphatidylserine a drug for the ageing brain? Pharmacol Res. 1996;33:73–80. - PubMed
    1. Vance JE, Steenbergen R. Metabolism and functions of phosphatidylserine. Prog Lipid Res. 2005;44:207–234. - PubMed

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