Abstract
Interferon-inducible protein 10 (IP-10) is a chemokine playing an important role in the restriction of viral spread. A time- and dose-dependent increase in IP-10 is found upon activation of viral receptors expressed on mesothelial cells, which provides novel evidence for a link between viral infections and inflammation of serous membranes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chemokine CXCL10 / metabolism*
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Epithelial Cells / immunology
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Epithelial Cells / metabolism*
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Epithelial Cells / virology
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Epithelium / immunology
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Epithelium / metabolism
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Epithelium / virology
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Humans
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RNA, Double-Stranded / chemical synthesis
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RNA, Double-Stranded / immunology*
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Receptors, Virus / metabolism
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Up-Regulation
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Virus Diseases / immunology*
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Viruses / immunology
Substances
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Chemokine CXCL10
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RNA, Double-Stranded
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Receptors, Virus