Characterization of a G-protein beta-subunit gene from the nematode Caenorhabditis elegans

J Mol Biol. 1990 May 5;213(1):17-26. doi: 10.1016/s0022-2836(05)80118-4.


The gene encoding the beta-subunit of guanine nucleotide binding regulatory proteins (G-proteins) has been cloned from the nematode Caenorhabditis elegans. The predicted 340 amino acid sequence matches the highly conserved amino acid sequences of previously isolated G-protein beta-subunits from mammals and Drosophila. The coding region of the C. elegans beta-subunit gene, which has been mapped to the C. elegans chromosome II, is interrupted by eight introns. Southern analysis indicates that C. elegans has only one beta-subunit gene. A 2.8 kb (1 kb = 10(3) bases or base-pairs) transcript derived from this gene could be detected.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Blotting, Northern
  • Blotting, Southern
  • Caenorhabditis / genetics*
  • Chromosome Mapping
  • Cloning, Molecular
  • DNA / genetics
  • GTP-Binding Proteins / genetics*
  • Genes
  • Molecular Sequence Data
  • Restriction Mapping
  • Sequence Homology, Nucleic Acid


  • DNA
  • GTP-Binding Proteins

Associated data

  • GENBANK/X17497