Hepatobiliary manifestations of critically ill and postoperative patients

Clin Liver Dis. 2011 Feb;15(1):183-97. doi: 10.1016/j.cld.2010.09.004.


Liver dysfunction is common in both the critically ill and postoperative patient. Metabolic derangements secondary to sepsis, poor hepatic perfusion, total parenteral nutrition, in addition to hemodynamic and anesthetic-induced changes that occur during surgery, can cause liver damage ranging from small self-limited abnormalities in liver chemistries to acute liver failure. Early recognition, supportive care, and effective treatment of the underlying disease process are crucial steps in managing liver disease in a critically ill patient.

Publication types

  • Review

MeSH terms

  • Biliary Tract Diseases / etiology*
  • Biliary Tract Diseases / physiopathology
  • Critical Care / methods
  • Critical Illness
  • Humans
  • Liver Diseases / etiology*
  • Liver Diseases / physiopathology
  • Postoperative Period