Constructing a fish metabolic network model

Genome Biol. 2010;11(11):R115. doi: 10.1186/gb-2010-11-11-r115. Epub 2010 Nov 29.

Abstract

We report the construction of a genome-wide fish metabolic network model, MetaFishNet, and its application to analyzing high throughput gene expression data. This model is a stepping stone to broader applications of fish systems biology, for example by guiding study design through comparison with human metabolism and the integration of multiple data types. MetaFishNet resources, including a pathway enrichment analysis tool, are accessible at http://metafishnet.appspot.com.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Computational Biology / methods
  • Fishes / genetics*
  • Gene Expression
  • Gene Expression Profiling*
  • Genome
  • Humans
  • Metabolic Networks and Pathways*
  • Models, Biological*
  • Oligonucleotide Array Sequence Analysis
  • Software*
  • Systems Biology*
  • User-Computer Interface