Exploring the links between natural products and bacterial assemblages in the sponge Aplysina aerophoba
- PMID: 21115701
- PMCID: PMC3028720
- DOI: 10.1128/AEM.00100-10
Exploring the links between natural products and bacterial assemblages in the sponge Aplysina aerophoba
Abstract
The sponge Aplysina aerophoba produces a large diversity of brominated alkaloids (BAs) and hosts a complex microbial assemblage. Although BAs are located within sponge cells, the enzymes that bind halogen elements to organic compounds have been exclusively described in algae, fungi, and bacteria. Bacterial communities within A. aerophoba could therefore be involved in the biosynthesis of these compounds. This study investigates whether changes in both the concentration of BAs and the bacterial assemblages are correlated in A. aerophoba. To do so, we quantified major natural products using high-performance liquid chromatography and analyzed bacterial assemblages using denaturing gradient gel electrophoresis on the 16S rRNA gene. We identified multiple associations between bacteria and natural products, including a strong relationship between a Chloroflexi phylotype and aplysinamisin-1 and between an unidentified bacterium and aerophobin-2 and isofistularin-3. Our results suggest that these bacteria could either be involved in the production of BAs or be directly affected by them. To our knowledge, this is one of the first reports that find a significant correlation between natural products and bacterial populations in any benthic organism. Further investigating these associations will shed light on the organization and functioning of host-endobiont systems such as Aplysina aerophoba.
Figures
Similar articles
-
Temporal trends in the secondary metabolite production of the sponge Aplysina aerophoba.Mar Drugs. 2012 Apr;10(4):677-693. doi: 10.3390/md10040677. Epub 2012 Mar 23. Mar Drugs. 2012. PMID: 22690137 Free PMC article.
-
Morphological, bacterial, and secondary metabolite changes of Aplysina aerophoba upon long-term maintenance under artificial conditions.Microb Ecol. 2009 Nov;58(4):865-78. doi: 10.1007/s00248-009-9560-6. Epub 2009 Jul 9. Microb Ecol. 2009. PMID: 19588186
-
Chemical defense of Mediterranean sponges Aplysina cavernicola and Aplysina aerophoba.Z Naturforsch C J Biosci. 2004 Jan-Feb;59(1-2):113-22. doi: 10.1515/znc-2004-1-222. Z Naturforsch C J Biosci. 2004. PMID: 15018063
-
Microbial diversity of marine sponges.Prog Mol Subcell Biol. 2003;37:59-88. doi: 10.1007/978-3-642-55519-0_3. Prog Mol Subcell Biol. 2003. PMID: 15825640 Review.
-
Recent Advances of Marine Sponge-Associated Microorganisms as a Source of Commercially Viable Natural Products.Mar Biotechnol (NY). 2022 Jun;24(3):492-512. doi: 10.1007/s10126-022-10130-2. Epub 2022 May 14. Mar Biotechnol (NY). 2022. PMID: 35567600 Review.
Cited by
-
Environmental heterogeneity and microbial inheritance influence sponge-associated bacterial composition of Spongia lamella.Microb Ecol. 2014 Oct;68(3):611-20. doi: 10.1007/s00248-014-0428-z. Epub 2014 May 7. Microb Ecol. 2014. PMID: 24801965
-
PLSDA-batch: a multivariate framework to correct for batch effects in microbiome data.Brief Bioinform. 2023 Mar 19;24(2):bbac622. doi: 10.1093/bib/bbac622. Brief Bioinform. 2023. PMID: 36653900 Free PMC article.
-
Roles of Organohalide-Respiring Dehalococcoidia in Carbon Cycling.mSystems. 2020 Jun 9;5(3):e00757-19. doi: 10.1128/mSystems.00757-19. mSystems. 2020. PMID: 32518199 Free PMC article.
-
Bacterial Communities Inhabiting the Sponge Biemna fortis, Sediment and Water in Marine Lakes and the Open Sea.Microb Ecol. 2018 Oct;76(3):610-624. doi: 10.1007/s00248-018-1156-6. Epub 2018 Feb 22. Microb Ecol. 2018. PMID: 29470608
-
Impact of the Cultivation Technique on the Production of Secondary Metabolites by Chrysosporium lobatum TM-237-S5, Isolated from the Sponge Acanthella cavernosa.Mar Drugs. 2019 Nov 30;17(12):678. doi: 10.3390/md17120678. Mar Drugs. 2019. PMID: 31801271 Free PMC article.
References
-
- Althoff, K., C. Schütt, R. Steffen, R. Batel, and W. E. G. Müller. 1998. Evidence for a symbiosis between bacteria of the genus Rhodobacter and the marine sponge Halichondria panicea: harbor also for putatively toxic bacteria? Mar. Biol. 130:529-536.
-
- Becerro, M. A. 2008. Quantitative trends in sponge ecology research. Mar. Ecol. Evol. Persp. 29:167-177.
-
- Becerro, M. A., V. Bonito, and V. J. Paul. 2006. Effects of monsoon-driven wave action on coral reefs of Guam and implications for coral recruitment. Coral Reefs 25:193-199.
Publication types
MeSH terms
Substances
Associated data
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
