Cytoskeletal dynamics in fission yeast: a review of models for polarization and division

HFSP J. 2010 Jun;4(3-4):122-30. doi: 10.2976/1.3385659. Epub 2010 Apr 15.


We review modeling studies concerning cytoskeletal activity of fission yeast. Recent models vary in length and time scales, describing a range of phenomena from cellular morphogenesis to polymer assembly. The components of cytoskeleton act in concert to mediate cell-scale events and interactions such as polarization. The mathematical models reduce these events and interactions to their essential ingredients, describing the cytoskeleton by its bulk properties. On a smaller scale, models describe cytoskeletal subcomponents and how bulk properties emerge.