Anticardiolipin syndrome in childhood: a report of two cases

Clin Exp Rheumatol. 1990 Jan-Feb;8(1):95-8.

Abstract

We describe two children with an otherwise unexplained deep vein thrombosis associated with high titer anticardiolipin antibodies (ACA) of the IgG class and circulating lupus anticoagulant (LAC). One of these patients had persistent proteinuria but neither had systemic lupus erythematosus. Our observation suggests that ACA and LAC assays should be performed in children with thromboembolic disease even when no underlying autoimmune disease can be found.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Autoantibodies / blood*
  • Autoimmune Diseases / immunology
  • Blood Coagulation Factors / immunology
  • Blood Coagulation Factors / isolation & purification
  • Cardiolipins / immunology*
  • Child
  • Humans
  • Lupus Coagulation Inhibitor
  • Lupus Erythematosus, Systemic / immunology
  • Male
  • Syndrome
  • Thrombophlebitis / immunology*

Substances

  • Autoantibodies
  • Blood Coagulation Factors
  • Cardiolipins
  • Lupus Coagulation Inhibitor