New hopane triterpenes and antioxidant constituents from Potentilla fulgens

Nat Prod Commun. 2010 Oct;5(10):1561-6.

Abstract

Phytochemical investigation of the aerial parts of Potentilla fulgens L. led to the isolation of two new triterpenes, potentene A (1) and potentene B (2). In addition, three known compounds afzelchin-4alpha --> 8"-catechin (3), epiafzelchin (4) and rutin (5) were isolated. The structures of all these compounds were elucidated by extensive spectroscopic and chemical evidence. Compounds 3, 4, and 5 exhibited significant 1,1,diphenyl-2-picrylhydrazyl radical scavenging activity, with IC50 values of 1.21, 2.88 and 5.20 mg/mL, respectively; the known standard antioxidant, vitamin C, had a value of 0.44 mg/mL.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / isolation & purification*
  • Catechin / analogs & derivatives
  • Catechin / isolation & purification
  • Flavonoids / isolation & purification
  • Potentilla / chemistry*
  • Rutin / isolation & purification
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*

Substances

  • Antioxidants
  • Flavonoids
  • Triterpenes
  • afzelchin-4'-8''-catechin
  • epiafzelechin
  • hopane
  • Rutin
  • Catechin