Abstract
Bisphenol A (BPA) is an endocrine disruptor with estrogenic properties that can adversely affect meiotic spindle assemblies. Our data indicate that BPA exposure in female patients may interfere with oocyte quality during IVF, as suggested by the inverse association between serum unconjugated BPA concentration and normal fertilization.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Publication types
-
Clinical Trial
-
Research Support, N.I.H., Extramural
MeSH terms
-
Adult
-
Benzhydryl Compounds
-
Endocrine Disruptors / analysis
-
Endocrine Disruptors / blood
-
Endocrine Disruptors / toxicity
-
Female
-
Fertilization / drug effects
-
Fertilization / physiology
-
Fertilization in Vitro*
-
Humans
-
Infertility / etiology
-
Infertility / therapy
-
Male
-
Oocytes / cytology*
-
Oocytes / drug effects*
-
Osmolar Concentration
-
Ovulation Induction / methods
-
Phenols / analysis
-
Phenols / blood*
-
Phenols / toxicity*
-
Pregnancy
-
Quality Control
Substances
-
Benzhydryl Compounds
-
Endocrine Disruptors
-
Phenols
-
bisphenol A