The Berlin Questionnaire for assessment of sleep disordered breathing risk in parturients and non-pregnant women

Int J Obstet Anesth. 2011 Jan;20(1):22-5. doi: 10.1016/j.ijoa.2010.09.010. Epub 2010 Nov 30.


Background: Pregnancy is associated with alteration in sleep patterns and quality. We wished to investigate whether pregnant women have a higher likelihood of a positive Berlin Questionnaire than non-pregnant women.

Methods: Pregnant women ages 18-45 years (n=4074) presenting for delivery, and non-pregnant women ages 18-45 years (n=490) presenting for outpatient surgery provided demographic information and completed the Berlin Questionnaire evaluating self-reported snoring and daytime sleepiness. For the pregnant patients, the infant's birth weight and Apgar scores were also recorded.

Results: Of the 1439 patients with a positive Berlin Questionnaire, 96 were in the non-pregnant control population versus 1343 in the pregnant population (20% vs. 33%, respectively, P<0.001; odds ratio 2.0 [95% CI: 1.6-2.5]). There was a positive correlation between infant weight and a positive Berlin Questionnaire. The incidence of preeclampsia was greater (odds ratio 3.9) in the pregnant patients with a positive Berlin Questionnaire as compared with the parturients with a negative Berlin Questionnaire (odds ratio 1.1).

Conclusion: Parturients are more likely to have a positive Berlin Questionnaire than non-pregnant women. This may indicate an increased likelihood of sleep disordered breathing.

MeSH terms

  • Adolescent
  • Adult
  • Apgar Score
  • Berlin
  • Cohort Studies
  • Disorders of Excessive Somnolence / epidemiology
  • Female
  • Humans
  • Middle Aged
  • Polysomnography
  • Pre-Eclampsia / epidemiology
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Pregnancy Complications / epidemiology
  • Prospective Studies
  • Sleep Apnea Syndromes / diagnosis*
  • Sleep Apnea Syndromes / epidemiology
  • Snoring / epidemiology
  • Surveys and Questionnaires*
  • Young Adult