Toward the synthesis of sequence-controlled vinyl copolymers

Chem Commun (Camb). 2011 Feb 7;47(5):1455-7. doi: 10.1039/c0cc04807k. Epub 2010 Dec 2.


An ATRA based strategy to synthesize vinyl copolymers with monomer-level sequence control is proposed. In each cycle, one allyl alcohol is added to the ATRP chain end, and then the hydroxymethyl residue is oxidized to carboxylic acid and a side group is introduced via esterification, making the new chain end active for the next cycle.