Hospitalizations due to respiratory syncytial virus in children with congenital malformations

Pediatr Infect Dis J. 2011 May;30(5):442-5. doi: 10.1097/INF.0b013e318201813b.


Statewide respiratory syncytial virus (RSV) lower respiratory tract infection hospitalization data of Colorado children with congenital malformations was used to estimate the population-based risk and severity of disease of RSV hospitalizations. Spina bifida without anencephaly, cleft palate, lung agenesis or dysgenesis, and biliary atresia were associated with a higher risk of being hospitalized with RSV lower respiratory tract infection and an increased severity of disease when hospitalized.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Colorado / epidemiology
  • Congenital Abnormalities*
  • Female
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Respiratory Syncytial Virus Infections / epidemiology*
  • Respiratory Syncytial Virus Infections / pathology
  • Respiratory Syncytial Virus, Human / isolation & purification*
  • Risk Factors
  • Young Adult