Melanocytic lesions of the conjunctiva

Arch Pathol Lab Med. 2010 Dec;134(12):1785-92. doi: 10.1043/2009-0522-RAR.1.


Context: Melanocytic proliferations are among the most common neoplasms of the conjunctiva. They often represent challenging lesions for pathologists unfamiliar with unique histologic features of melanocytic proliferations in this location and with nomenclature used by ophthalmologists.

Objective: To comprehensively review clinical aspects, pathologic features, and management of melanocytic proliferations of the conjunctiva.

Data sources: Review of the literature and personal experience of the authors.

Conclusions: Classification, state of the art, and practical aspects of pathology of melanocytic proliferations of the conjunctiva are discussed.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / metabolism
  • Cell Proliferation
  • Conjunctival Neoplasms / classification
  • Conjunctival Neoplasms / metabolism
  • Conjunctival Neoplasms / pathology*
  • Humans
  • Melanocytes / metabolism
  • Melanocytes / pathology*
  • Melanoma / classification
  • Melanoma / metabolism
  • Melanoma / pathology*
  • Melanosis / metabolism
  • Melanosis / pathology*
  • Nevus / classification
  • Nevus / metabolism
  • Nevus / pathology*


  • Biomarkers, Tumor