Effect of sleeve gastrectomy on gastroesophageal reflux disease: a systematic review

Surg Obes Relat Dis. Jul-Aug 2011;7(4):510-5. doi: 10.1016/j.soard.2010.09.011. Epub 2010 Sep 21.


Background: Sleeve gastrectomy (SG) has increased in popularity as both a definitive and a staged procedure for morbid obesity. Gastroesophageal reflux disease (GERD) is a common co-morbid disease in bariatric patients. The effect of SG on GERD has not been well studied; thus, the goal of the present systematic data review was to analyze the effect of SG on GERD.

Methods: A systematic data search was conducted using Medline, EMBASE, the Cochrane Database, Scopus, and the gray literature for the Keywords "sleeve gastrectomy;" "gastroesophageal reflux;" and equivalents.

Results: A total of 15 reports were retrieved. Two reports analyzed GERD as a primary outcome, and 13 included GERD as a secondary study outcome. Of the 15 studies, 4 showed an increase in GERD after SG, 7 found reduced GERD prevalence after SG, 3 included only the postoperative prevalence of GERD, and 1 did not include data on prevalence of GERD.

Conclusion: The evidence of the effect of SG on GERD did not consolidate to a consensus. The studies showed differing outcomes. Hence, dedicated studies that objectively evaluate GERD after SG are needed to more clearly define the effect of SG on GERD in bariatric patients.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Gastrectomy / methods*
  • Gastroesophageal Reflux / etiology
  • Gastroesophageal Reflux / surgery*
  • Humans
  • Obesity, Morbid / complications
  • Obesity, Morbid / surgery*
  • Weight Loss