Pediatric cannabinoid hyperemesis: two cases

Pediatr Emerg Care. 2010 Dec;26(12):919-20. doi: 10.1097/PEC.0b013e3181fe9189.

Abstract

Cannabinoid hyperemesis has recently been described in the literature. It is a syndrome characterized by severe nausea and hyperemesis in the setting of chronic marijuana abuse and, to date, has been described only in adults. We describe the syndrome in 2 pediatric patients, for whom extensive gastrointestinal workups failed to identify a clear cause and cessation of marijuana use resulted in the alleviation of their symptoms. As in most published adult cases, compulsive bathing was present in both of these cases.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Asthmatic Agents / therapeutic use
  • Antidepressive Agents / therapeutic use
  • Asthma / complications
  • Asthma / drug therapy
  • Attention Deficit Disorder with Hyperactivity / complications
  • Baths
  • Cannabis / adverse effects*
  • Comorbidity
  • Depressive Disorder / complications
  • Depressive Disorder / drug therapy
  • Female
  • Humans
  • Male
  • Marijuana Abuse / complications*
  • Marijuana Smoking / adverse effects*
  • Nausea / chemically induced
  • Nausea / therapy
  • Receptor, Cannabinoid, CB1 / drug effects
  • Receptor, Cannabinoid, CB1 / physiology
  • Tobacco Use Disorder / complications
  • Vomiting / chemically induced*
  • Vomiting / prevention & control

Substances

  • Anti-Asthmatic Agents
  • Antidepressive Agents
  • Cnr1 protein, rat
  • Receptor, Cannabinoid, CB1