Multiple sclerosis: Lesion location may predict disability in multiple sclerosis

Nat Rev Neurol. 2010 Dec;6(12):648-9. doi: 10.1038/nrneurol.2010.161.


Lesion location might turn out to be an important factor in long-term disability prediction in patients with primary progressive multiple sclerosis (MS). Using a lesion probability mapping approach, researchers have identified brain regions where the presence of MS lesions predicts an early need for bilateral walking support.

Publication types

  • News

MeSH terms

  • Brain / pathology*
  • Disability Evaluation*
  • Humans
  • Magnetic Resonance Imaging*
  • Multiple Sclerosis / pathology*
  • Multiple Sclerosis / physiopathology
  • Predictive Value of Tests
  • Prognosis